NFL

San Francisco 49ers at Buffalo Bills

· National Football League
5-5, 2-2 Away

vs
9-2, 5-0 Home

How can I watch 49ers vs. Bills?

  • TV Channel: 49ers at Bills 2021-22 NFL, week 13 is broadcasted nationally on NBC and Peacock.
  • Online streaming: Sign up for Fubo.
    In Canada, viewers can watch 49ers vs. Bills on DAZN.

Statistics

https://a.espncdn.com/combiner/i?img=/i/teamlogos/nfl/500/sf.png&h=100&scale=crop&w=100&location=originSF https://a.espncdn.com/combiner/i?img=/i/teamlogos/nfl/500/buf.png&h=100&scale=crop&w=100&location=originBUF
25.0 Points Per Game 29.1
409.1 Total Yards 350.8
261.3 Yards Passing 231.6
147.8 Yards Rushing 119.2
22.2 Points Allowed Per Game 19.5
315.1 Yards Allowed 345.9
210.1 Pass Yards Allowed 226.8
105.0 Rush Yards Allowed 119.1
Buffalo Bills Buffalo Bills Injuries
NAME, POS STATUS DATE
Dalton Kincaid, TE Out Nov 19
Keon Coleman, WR Out Nov 19
Spencer Brown, OT Out Nov 17
Matt Milano, LB Injured Reserve Nov 15
Baylon Spector, LB Injured Reserve Nov 9
San Francisco 49ers San Francisco 49ers Injuries
NAME, POS STATUS DATE
Nick Bosa, DE Questionable Nov 20
Jacob Cowing, WR Questionable Nov 20
George Kittle, TE Questionable Nov 20
Brock Purdy, QB Questionable Nov 20
Tatum Bethune, LB Doubtful Nov 19

Game Information

Highmark Stadium

Location: Orchard Park, NY
Capacity:

2024 NFC West Standings

TEAM W L PCT T PF PA
Arizona 6 4 .600 0 238 220
Los Angeles 5 5 .500 0 213 239
Seattle 5 5 .500 0 230 238
San Francisco 5 5 .500 0 250 222

2024 AFC East Standings

TEAM W L PCT T PF PA
Buffalo 9 2 .818 0 320 214
Miami 4 6 .400 0 181 221
New York 3 8 .273 0 204 242
New England 3 8 .273 0 182 248
Full Standings

49ers Last 5

Date OPP Result
@ SEA W 36-24
vs KC L 28-18
vs DAL W 30-24
@ TB W 23-20
vs SEA L 20-17

Bills Last 5

Date OPP Result
vs TEN W 34-10
@ SEA W 31-10
vs MIA W 30-27
@ IND W 30-20
vs KC W 30-21

NFL News

Orlovsky: Steelers need to fix their red zone offense immediately

Orlovsky: Steelers need to fix their red zone offense immediately

Dan Orlovsky, Mike Greenberg and Adam Schefter analyze what the Steelers need to change offensively to be a Super Bowl contender.

2025 NFL mock drafts: Latest ESPN player, team predictions

2025 NFL mock drafts: Latest ESPN player, team predictions

Here are our experts' NFL mock drafts for the 2025 cycle, including projected landing spots for Shedeur Sanders and Luther Burden III.

Week 12 matchup rankings: Chargers have recipe for fantasy success

Week 12 matchup rankings: Chargers have recipe for fantasy success

Matchups are a driving force behind weekly lineup decisions in fantasy football. Here are the most and least favorable matchups in the NFL at QB, RB, WR and TE for Week 12.

2025 NFL mock draft: Predicting all 32 first-round picks

2025 NFL mock draft: Predicting all 32 first-round picks

An early run on receivers? Four QBs in the first round? A trade for the top pick? Matt Miller projects the opening 32 selections of April's draft.

Is Buccaneers WR Mike Evans' 1,000-yard streak in jeopardy?

Is Buccaneers WR Mike Evans' 1,000-yard streak in jeopardy?

After missing three games, Evans needs 665 yards in seven games to extend his 1,000-yard season streak to 11.