
Arizona Cardinals at San Francisco 49ers
· National Football LeagueKyler Murray rallies the Cardinals past the 49ers, 24-23
It ended with him driving the Arizona Cardinals into field goal position and then becoming a spectator watching his team's fill-in kicker and defense come through at the end.
Both delivered with Chad Ryland kicking a 35-yard field goal with 1:37 to play and Kyzir White intercepting a pass from Brock Purdy to seal Arizona's 24-23 comeback victory over the San Francisco 49ers on Sunday.
“I hated it,” Murray said about the game being out of his control at the end. “I didn’t want to give them the ball back. I was hoping we could convert and end the games on our terms. That didn’t happen. Chad was great making the field goal and the defense came up clutch.”
Murray did plenty with his touchdown run, touchdown pass and key late drive but he also had plenty of help. James Conner ran for 86 yards and scored on a 2-point conversion, Marvin Harrison Jr. made a fourth-down catch to fuel the winning drive and the defense pitched a second-half shutout with three takeaways.
It was a far cry from a week ago when the Cardinals (2-3) were embarrassed in a 42-14 loss at home to Washington.
“We wanted to get it to the fourth quarter and have a chance to win the game, and that’s what we did,” coach Jonathan Gannon said. “Last week was not a good performance by us. They took that some type of way.”
This marked the second time this season that San Francisco (2-3) blew a double-digit lead in the fourth quarter to a division rival, having done it in Week 3 Los Angeles Rams.
The Niners lost just one division game the past two season when winning NFC West titles but are 0-2 already this year after the sixth blown double-digit lead in the fourth quarter in the regular season and playoffs under coach Kyle Shanahan.
“In the second half, we kind of melted down,” All-Pro linebacker Fred Warner said. “Too much leaky yardage, missed tackles, not fitting it right.”
Murray threw for 195 yards and a TD and added 82 yards rushing.
The 49ers squandered several chances and scored only one TD on six drives that reached the end zone. The most costly came midway through the fourth quarter when Jordan Mason lost a fumble that Mack Wilson recovered at the 8 to keep Arizona within two points.
Murray then led the winning drive. On the key play to Harrison, Murray flung a pass under pressure that the rookie receiver hauled in for a 14-yard completion into Niners territory. The Cardinals then ran five straight times to set up the field goal by Ryland, who quickly won over his teammates after being signed this week to fill in for the injured Matt Prater.
“They were going nuts in the locker room,” Gannon said. “Half the guys didn’t even know him.”
Purdy went 18 for 33 for 229 yards, one touchdown and one interception for the 49ers, who managed only one offensive touchdown with the other TD coming on a blocked field goal return.
The Cardinals started fast by forcing a three-and-out to open the game and getting a 50-yard TD run from Murray on their second play from scrimmage.
The 49ers controlled the rest of the half with Purdy throwing a 4-yard TD to George Kittle and Deommodore Lenoir returning a blocked field goal by Jordan Elliott for a 61-yard score that helped San Francisco take a 23-10 lead at the break.
49ers: K Jake Moody left the game in the second quarter with a high right ankle sprain after getting hurt on a tackle on a kick return. P Mitch Wishnowsky hit a 26-yard FG at the end of the first half but the Niners opted to go for it in the third quarter on fourth and 23 from the 27. ... S Talanoa Hufanga (wrist) also left in the first half.
49ers: At Seattle on Thursday night.
How can I watch Cardinals vs. 49ers?
- TV Channel: Cardinals at 49ers 2021-22 NFL, week 5 is broadcasted nationally on FOX and NFL Sunday Ticket.
- Online streaming: Sign up for Fubo.
In Canada, viewers can watch Cardinals vs. 49ers on DAZN.
Scoring Summary
![]() |
TD | 1st Period 13:12 | Kyler Murray 50 Yd Run (Chad Ryland Kick) |
![]() |
FG | 1st Period 10:25 | Jake Moody 28 Yd Field Goal |
![]() |
TD | 1st Period 2:20 | George Kittle 4 Yd pass from Brock Purdy (Jake Moody Kick) |
![]() |
FG | 2nd Period 12:43 | Chad Ryland 30 Yd Field Goal |
![]() |
FG | 2nd Period 6:59 | Jake Moody 20 Yd Field Goal |
![]() |
TD | 2nd Period 4:59 | Deommodore Lenoir 61 Yd Return of Blocked Field Goal (Jake Moody Kick) |
![]() |
FG | 2nd Period 0:00 | Mitch Wishnowsky 26 Yd Field Goal |
![]() |
FG | 3rd Period 9:59 | Chad Ryland 42 Yd Field Goal |
![]() |
TD | 4th Period 11:25 | Elijah Higgins 2 Yd pass from Kyler Murray (James Conner Run for Two-Point Conversion) |
![]() |
FG | 4th Period 1:37 | Chad Ryland 35 Yd Field Goal |
Statistics
![]() |
![]() |
|
---|---|---|
19 | 1st Downs | 22 |
10 | Passing 1st downs | 13 |
9 | Rushing 1st downs | 9 |
0 | 1st downs from penalties | 0 |
3-10 | 3rd down efficiency | 6-11 |
1-1 | 4th down efficiency | 0-1 |
57 | Total Plays | 63 |
358 | Total Yards | 384 |
6.3 | Yards per Play | 6.1 |
10 | Total Drives | 9 |
189 | Passing | 231 |
19/30 | Comp/Att | 19/35 |
6.1 | Yards per pass | 6.2 |
1 | Interceptions thrown | 2 |
1-6 | Sacks-Yards Lost | 2-13 |
169 | Rushing | 153 |
26 | Rushing Attempts | 26 |
6.5 | Yards per rush | 5.9 |
1-3 | Red Zone (Made-Att) | 1-6 |
1-5 | Penalties | 4-21 |
1 | Turnovers | 3 |
0 | Fumbles lost | 1 |
1 | Interceptions thrown | 2 |
0 | Defensive / Special Teams TDs | 1 |
27:02 | Possession | 32:58 |
San Francisco 49ers Injuries
NAME, POS | STATUS | DATE |
---|---|---|
Brandon Aiyuk, WR | Questionable | Mar 31 |
Tre Brown, CB | Questionable | Mar 13 |
Kevin Givens, DT | Questionable | Mar 10 |
Trent Williams, OT | Questionable | Feb 26 |
Mitch Wishnowsky, P | Questionable | Feb 12 |
Arizona Cardinals Injuries
NAME, POS | STATUS | DATE |
---|---|---|
Emari Demercado, RB | Questionable | Feb 17 |
Jonah Williams, OT | Questionable | Feb 10 |
BJ Ojulari, LB | Questionable | Feb 10 |
Bilal Nichols, DT | Questionable | Feb 10 |
Elijah Jones, CB | Questionable | Feb 10 |
Game Information

Location: Santa Clara, CA
Attendance: 71,310 · Capacity:
2024 NFC West Standings
TEAM | W | L | PCT | T | PF | PA |
---|---|---|---|---|---|---|
Los Angeles | 10 | 7 | .588 | 0 | 367 | 386 |
Seattle | 10 | 7 | .588 | 0 | 375 | 368 |
Arizona | 8 | 9 | .471 | 0 | 400 | 379 |
San Francisco | 6 | 11 | .353 | 0 | 389 | 436 |
NFL News

Stephen A., Orlovsky argue about which Colorado star the Giants should take
Stephen A. Smith and Dan Orlovsky go back and forth on the Giants' needs and who fits best between Shedeur Sanders and Travis Hunter.

Canty: Cowboys have to start considering a Dak Prescott trade
Chris Canty explains why the Cowboys' lack of playoff success will pressure them to consider trading Dak Prescott.

2025 NFL draft: Latest buzz, Hunter's position, sleepers
Could Travis Hunter play full-time wide receiver? Which teams are most likely to trade down? Our NFL draft experts weigh in.

How Cowboys get a draft advantage with their 'Dallas Day'
With many draft prospects from the Dallas area -- such as RB Ashton Jeanty and QB Quinn Ewers -- the Cowboys have a leg up on other NFL teams.

Detroit Lions prioritized discipline in NFL free agency
With so many young stars still to pay, the Lions are trusting what they already had in-house this offseason.